August 2014



There is a new treatment now being utilized for cardiovascular protection that is similar to EDTA called Plaquex. The Plaquex program involves administration of a phospholipid to help reduce plaque build up in the walls of arteries. The essential phospholipid is called phosphatidylcholine or lecithin. Dermatologists and cosmetic surgeons have recently started using phosphatidylcholine injections to selectively break down fat deposits under the skin. However the idea has been around for years and used extensively throughout Europe where studies first indicated it would remove fat from the inside of blood vessels. This therapy is becoming more popular in chelation clinics where it is now being used in conjunction with EDTA chelation

EDTA chelation is important for many reasons but primarily for removing the metals and minerals that oxidize cholesterol (damage the cholesterol and allow it to become harmful). It is the oxidized cholesterol that causes inflammation of the blood vessel wall that causes plaque to form. Chelation also shrinks established plaque which is how it improves symptoms. Therefore chelation should be thought of more as a preventive treatment. The Plaquex is synergistic with chelation, that is it helps to remove established plaque as opposed to being preventive. The Plaquex helps to remove fat deposits in the blood vessels by its effect on the lipid membrane of the cells in the arteries. This lipid membrane is where the plaque forms and this plaque is increased by deposition of abnormal fats or trans fatty acids. The Plaquex allows for an exchange of good fats for bad fats which tends to smooth out or shrink the plaque. Therefore the Plaquex is more useful for patients that have symptoms of angina, leg claudication, or heavy plaque buildup seen on x-rays. Plaque is a complex substance that is impossible to entirely remove, however it be decreased and prevented from increasing.

Plaquex is administered in an IV as is chelation and the treatment typically takes 2 hours. The number of treatments depends on symptoms and disease severity, but averages between 20 to 30, as does chelation. The improvement is a slow proves and related to changes in the lipid composition of cells and blood vessels. Chelation and Plaquex cannot be administered together and therefore require administration in different days. If patients have no symptoms of angina or pain, then we recommend a chelation series first followed by a series of Plaquex treatments. If one does have symptoms, then we recommend one treatment of each per week For severe symptoms we recommend 2 Plaquex treatments per week along with one EDTA.

In summary, Plaquex has been shown to reduce plaque that causes:

  • Coronary artery disease
  • Heart attacks
  • Strokes
  • Angina
  • Leg claudication pain
  • Diabetic complications
  • Neuropathy Hypertension

Plaquex involves administration of essential phospholipids (phosphatidylcholine) by IV infusion to reverse the plaque build up in blood vessels by a lipid exchange mechanism of good fats for bad fats in lipid membranes.

To go to the next article in this series Stress Reduction Programs, click here.